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20072026

Research activity per year

Personal profile

Personal profile

Treatment Philosophy

I am excited to be a part of the gynecologic cancer patient care team at Fox Chase Cancer Center. I chose to work at Fox Chase to provide comprehensive, cutting-edge oncologic care by translating advances in research directly into my clinical practice.

As a gynecologic oncologist, I specialize in the surgical and medical management of tumors of the uterus, cervix, ovary, fallopian tube, vulva and vagina. I have extensive experience with complex open, laparoscopic and robotic surgery, which allows me to tailor a surgical plan based upon a patient’s needs and preferences. I also have expertise in administering intravenous and intraperitoneal chemotherapy for gynecologic malignancies. As a member of the multidisciplinary gynecologic cancer patient care team, I work closely with my colleagues in medical and radiation oncology to develop a comprehensive treatment plan that offers the best chance of cure for each patient.

I appreciate the challenges and commitment necessary to care for cancer patients. I understand that a cancer diagnosis can be overwhelming for patients and their families, and I always treat patients how I would want my family members to be treated: with honesty and compassion. I devote the time necessary to educate my patients on their options so they are best able to make an informed decision about their treatment.

Professionally, my research interests focus on endometriosis-associated ovarian cancer and hereditary ovarian cancer, including those resulting from BRCA1 or 2 mutations. The abundant resources available at Fox Chase, as well as my research experiences during my postdoctoral fellowship at the Magee-Womens Research Institute and as a clinical fellow at the University of Pennsylvania allow for me to participate in translational research and investigate innovative therapies to improve the quality of life for women with gynecologic malignancies.

Treatment Focus

Minimally invasive surgery (laparoscopy and robotic surgery); endometrial cancer and hyperplasia; cervical cancer and dysplasia; vulvar cancer and dysplasia; vaginal cancer and dysplasia; gestational trophoblastic disease; surgical management of pelvic masse

Areas of Expertise

Endometrial (Uterine) Cancer, Vulvar Cancer, Cervical Cancer, Uterine Sarcoma, Ovarian & Primary Peritoneal Cancer

Research interests

  • Fertility and gynecologic cancers
  • Endometriosis-related ovarian cancer
  • Hereditary ovarian cancer
  • Immunotherapy and ovarian cancer

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Collaborations and top research areas from the last five years

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  • Vaginal Cancer, Version 2.2026, NCCN Clinical Practice Guidelines In Oncology

    Abu-Rustum, N. R., Campos, S. M., Amarnath, S., Arend, R., Barber, E., Bradley, K., Brooks, R., Chino, J., Chon, H. S., Crispens, M. A., Damast, S., Fisher, C. M., Frederick, P., Gaffney, D. K., Gaillard, S., Giuntoli, R., Glaser, G., Glaser, S., Howitt, B. E. & Kendra, K. & 21 others, Landrum, L., Lea, J., Lee, N., Mantia-Smaldone, G., Mariani, A., Mutch, D., Nagel, C., Nekhlyudov, L., Nwachukwu, C., Podoll, M., Rodabaugh, K., Salani, R., Schorge, J., Schuetze, S., Siedel, J., Soliman, P., Ueda, S., Urban, R., Wyse, E., McMillian, N. & Sambandam, V., Mar 1 2026, In: Journal of the National Comprehensive Cancer Network : JNCCN. 24, 3, p. 101-126 26 p.

    Research output: Contribution to journalArticlepeer-review

  • Cervical Cancer, Version 2.2026, NCCN Clinical Practice Guidelines In Oncology: Cervical Cancer, Version 2.2026

    Abu-Rustum, N. R., Campos, S. M., Amarnath, S., Arend, R., Barber, E., Bradley, K., Brooks, R., Chino, J., Chon, H. S., Crispens, M. A., Damast, S., Fisher, C. M., Frederick, P., Gaffney, D. K., Gaillard, S., Giuntoli, R., Glaser, S., Howitt, B. E., Kendra, K. & Landrum, L. & 22 others, Lea, J., Lee, N., Mantia-Smaldone, G., Mariani, A., Mutch, D., Nagel, C., Nekhlyudov, L., Nieto, K., Nwachukwu, C., Podoll, M., Rodabaugh, K., Salani, R., Schorge, J., Schuetze, S., Siedel, J., Sisodia, R., Soliman, P., Ueda, S., Urban, R., Wyse, E., McMillian, N. & Sambandam, V., Dec 2025, In: Journal of the National Comprehensive Cancer Network. 23, 12, p. 549-573 25 p.

    Research output: Contribution to journalArticlepeer-review

    15 Scopus citations
  • Juntas Contra el Virus del Papiloma Humano: protocol for a pilot randomized controlled trial of an HPV self-sampling intervention for underscreened Latinas

    Fang, C. Y., Cora-Cruz, M., Koirala, P., Perez, S., Li, M., Egleston, B. L., Chen, Y., Mantia-Smaldone, G. & Martinez, O., May 10 2025, In: Pilot and Feasibility Studies. 11, 1, p. 65 65.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • NCCN Guidelines® Insights: Uterine Neoplasms, Version 3.2025

    Abu-Rustum, N. R., Campos, S. M., Amarnath, S., Arend, R., Barber, E., Bradley, K., Brooks, R., Chino, J., Chon, H. S., Crispens, M. A., Damast, S., Fisher, C. M., Frederick, P., Gaffney, D. K., Gaillard, S., Giuntoli, R., Glaser, S., Howitt, B. E., Landrum, L. & Lea, J. & 21 others, Lee, N., Mantia-Smaldone, G., Mariani, A., Mutch, D., Nagel, C., Nekhlyudov, L., Nieto, K., Nwachukwu, C., Podoll, M., Rodabaugh, K., Salani, R., Schorge, J., Schuetze, S., Siedel, J., Sisodia, R., Soliman, P., Ueda, S., Urban, R., Wyse, E., McMillian, N. & Sambandam, V., Aug 2025, In: JNCCN Journal of the National Comprehensive Cancer Network. 23, 8, p. 284-291 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    49 Scopus citations
  • Phase 1b study of mirvetuximab soravtansine, a folate receptor alpha (FRα)–targeting antibody-drug conjugate, in combination with carboplatin and bevacizumab in patients with platinum-sensitive ovarian cancer

    Richardson, D. L., Moore, K. N., Vergote, I., Gilbert, L., Martin, L. P., Mantia-Smaldone, G. M., Castro, C. M., Provencher, D., Matulonis, U. A., Stec, J., Wang, Y., Method, M. & O'Malley, D. M., Jun 2024, In: Gynecologic Oncology. 185, p. 186-193 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    37 Scopus citations