Research output per year
Research output per year
Personal profile
Research interests
I am interested in exploring the causes of Small Cell Lung Cancer (SCLC), as well as developing novel therapies for both SCLC and other recalcitrant cancers. I am currently studying unique vulnerabilities for SCLC governed by neuroendocrine differentiation as well as faulty cell cycle transition dynamics.
Lab Overview
The Schultz lab aims to further understand small cell lung cancer and unique vulnerabilities associated with neuroendocrine differentiation and characteristic mutations present in small cell lung cancer. All work at the Schultz lab is designed to be translationally relevant, with every project aimed at near-term translatability to the clinic if successful.
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Collaborations and top research areas from the last five years
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Genomic alterations and transcriptional phenotypes in circulating free DNA and matched metastatic tumor
Takahashi, N., Pongor, L., Agrawal, S. P., Shtumpf, M., Gurjar, A., Rajapakse, V. N., Shafiei, A., Schultz, C. W., Kim, S., Roame, D., Carter, P., Vilimas, R., Nichols, S., Desai, P., Figg Sr, W. D., Bagheri, M., Teif, V. B. & Thomas, A., Feb 25 2025, In: Genome Medicine. 17, 1, 16 p., 15.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Lamin A/C Deficiency Drives Genomic Instability and Poor Survival in Small-Cell Lung Cancer through Increased R-loop Accumulation
Schultz, C. W., Saha, S., Dhall, A., Zhang, Y., Desai, P., Pongor, L. S., Scheiblin, D. A., Magidson, V., Sun, Y., Redon, C., Kumar, S., Krishnamurthy, M., Dias, H. B., Aksenova, V., Giordano, E., Takahashi, N., Nirula, M., Arora, M., Tabe, C. & Thomas, M. & 10 others, , May 3 2025, (bioRxiv : the preprint server for biology).Research output: Working paper › Preprint
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Lamin A/C loss promotes R-loop-mediated genomic instability and poor survival in small-cell lung cancer
Schultz, C. W., Saha, S., Dhall, A., Zhang, Y., Desai, P., Pongor, L. S., Scheiblin, D. A., Magidson, V., Shuklah, R. P., Sebastian, R., Vekariya, U. M., Ahmed, S., Sun, Y., Redon, C., Kumar, S., Krishnamurthy, M., Dias, H. B., Aksenova, V., Giordano, E. & Takahashi, N. & 16 others, , Oct 28 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 43, p. e2503387122 e2503387122.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Metastatic organotropism in small cell lung cancer
Krishnamurthy, M., Dhall, A., Sahoo, S., Schultz, C. W., Baird, M. A., Desai, P., Odell, J., Takahashi, N., Nirula, M., Zhuang, S., Huang, Y., Schroeder, B., Zhang, Y., Thomas, M. S., Redon, C., Robinson, C., Thang, L., Ileva, L., Patel, N. L. & Kalen, J. D. & 18 others, , Jan 24 2025, (bioRxiv : the preprint server for biology).Research output: Working paper › Preprint
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SurvSig: Harnessing gene expression signatures to uncover heterogeneity in lung neuroendocrine neoplasms
Nemes, K., Fur, G. M., Beno, A., Schultz, C. W., Topolcsanyi, P., Mago, E., Desai, P., Takahashi, N., Aladjem, M. I., Reinhold, W., Pommier, Y., Thomas, A. & Pongor, L. S., Jan 2025, In: Computational and Structural Biotechnology Journal. 27, p. 2574-2583 10 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations