Research output per year
Research output per year
Personal profile
Personal profile
Treatment Philosophy
I believe that the path towards treating any disease is best navigated by thoroughly understanding not only the disease, but also the patient. Good communication between a physician and a patient is especially critical in the treatment of cancer. Each patient has a right to be both respected and heard. In addition, relying on a team of experts to help manage the complexities of treating cancer is essential for success. As a physician, I strive to provide personalized and scientifically sound care to each of my patients.
My medical career started out as a pharmacist, specializing in oncology, where I prepared chemotherapy regimens and studied the effects the body has on drugs (pharmacokinetics). When I went to medical school, it was for the sole purpose of eventually becoming an oncologist. During my hematology/oncology and clinical pharmacology fellowships, I spent a great deal of time in early clinical development, with a goal of finding new effective therapies for patients with cancer. I honed my knowledge of drug discovery by spending five years in the pharmaceutical industry where I led multiple programs aimed at treating patients with cancers that didn’t respond to traditional chemotherapy. Today, my interests focus on early drug development for all types of cancers, and understanding how each medication may best be used. In addition I specifically focus on the treatment of lung cancer, skin cancers including melanoma, and gastrointestinal malignancies.
In many situations, the best medical care a patient with cancer can get is on a clinical trial. These clinical trials offer patients potentially promising new therapies and very close follow up supplied by a team of experts. Fox Chase Cancer Center, with its leading-edge technology and dedicated medical professionals, offers numerous clinical trials and is helping to advance the care of all patients with cancer.
The staff at Fox Chase Cancer Center continually impress me with their unified commitment towards reducing the burden of cancer. When you step through the doors at Fox Chase Cancer Center, it is obvious that focusing on the patient is the top priority. I am proud to be a member of the caring community at FCCC, where oncology research and science is tailored and personalized for each patient.
Areas of Expertise
Thymoma, Esophageal Cancer, Lung Metastases, Neuroendocrine Tumors, Stomach (Gastric) Cancer, Endobronchial Disease, Lung Cancer, Mesothelioma, Skin Cancer, Colorectal Cancer, Liver, Gall Bladder & Bile Duct Cancer, Melanoma, Pancreatic Cancer
Treatment Focus
Early Clinical Drug Development/Phase 1 Trials; Melanoma and skin cancer; Lung cancers; Gastrointestinal cancers
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A phase I, first-in-human trial of KO-947, an ERK1/2 inhibitor, in patients with advanced solid tumors
Schram, A. M., Boni, V., Adjei, A. A., Olszanski, A. J., Vieito, M., Francis, J. H., Kurman, M., Ahsan, J. M., Tomkinson, B. & Garralda, E., Mar 2025, In: ESMO Open. 10, 3, p. 104300 104300.Research output: Contribution to journal › Article › peer-review
Open Access -
Recurrent Melanoma in a Patient with Chronic Lymphocytic Leukemia (CLL) Presenting with an Apparent Co-Existing NRAS and BRAF Mutation: A Diagnostic and Treatment Conundrum
Berardi, G. G., Muthanna, J., Wang, Y. L. & Olszanski, A. J., Jan 25 2025, In: International Journal of Molecular Sciences. 26, 3, 1029.Research output: Contribution to journal › Article › peer-review
Open Access -
Annals of Surgical Oncology Practice Guidelines Series: Adjuvant and Neoadjuvant Therapy for Melanoma
Farma, J. M., Olszanski, A. J., Messina, J. L. & Sondak, V. K., Oct 4 2024, (E-pub ahead of print) In: Annals of Surgical Oncology. 32, 1, p. 3-11 9 p., 112914.Research output: Contribution to journal › Review article › peer-review
Open Access -
A phase Ib study evaluating the recommended phase II dose, safety, tolerability, and efficacy of mivavotinib in combination with nivolumab in advanced solid tumors
Juric, D., Barve, M., Vaishampayan, U., Roda, D., Calvo, A., Jañez, N. M., Trigo, J., Greystoke, A., Harvey, R. D., Olszanski, A. J., Opyrchal, M., Spira, A., Thistlethwaite, F., Jiménez, B., Sappal, J. H., Kannan, K., Riley, J., Li, C., Li, C. & Gregory, R. C. & 2 others, , Mar 2024, In: Cancer Medicine. 13, 5, CAM46776.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Management of Immunotherapy-Related Toxicities, Version 2.2024 Featured Updates to the NCCN Guidelines
Thompson, J. A., Schneider, B. J., Brahmer, J., Zaid, M. A., Achufusi, A., Armand, P., Berkenstock, M. K., Bermas, B., Braaten, T., Budde, L. E., Chokshi, S., Crees, Z. D., Davies, M., Deng, C., Gesthalter, Y., Jain, M., Jain, P., Jallouk, A., Kaffenberger, B. H. & Khalil, M. & 25 others, , Nov 2024, In: JNCCN Journal of the National Comprehensive Cancer Network. 22, 9, p. 582-592 11 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations
Press/Media
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Philadelphia Magazine Names 142 Fox Chase Cancer Center Physicians 'Top Doctors'
Mantia-Smaldone, G. M., Vijayvergia, N., Borghaei, H., Weiss, S. E., Bodor, J. N., Kumar, R., Khanal, R., Frosch, Z. A., Flieder, D. B., Chen, D. Y., Plimack, E. R., Manley, C. J., Nejati, R. M., Ehya, H., Kutikov, A., Rubin, S. C., Sherry, D. R., Hallman, M. A., Uzzo, R. G., Patel, S. A., Daly, M., Viterbo, R., Curcillo, P. G., Bleicher, R., Wong, J. K., Reddy, S. S., Edelman, M., Nakhoda, S. K., Greco, S. H., Miyamoto, C. T., Bauman, J., von Mehren, M., Yu, J. Q., Chwistek, M., Galloway, T. J., Williams, A. D., Jain, A., Meyer, J. E., Castellanos, J. A., Hall, M. J., Ahmad, D., Farma, J. M., Weinberg, D. S., Friedberg, J., Wasik, M. A., Zibelman, M. R., Wang, Y. L., Geynisman, D., Astsaturov, I., Olszanski, A. J., Simhan, J., Friedlander, J. I., Cohn, J., Sterious, S., Ghiraldi, E. M., Wei, S., Aphale, A., McShane, M. M., Kumar, S. S., Walchak, A., Giri, A. P., Sharda, P. & Messmer, M.
04/22/25
1 item of Media coverage
Press/Media
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Data on Chronic Lymphocytic Leukemia Reported by Researchers at Fox Chase Cancer Center [Recurrent Melanoma In a Patient With Chronic Lymphocytic Leukemia (Cll) Presenting With an Apparent Co-existing Nras and Braf Mutation: a Diagnostic and ...]
Wang, Y. L. & Olszanski, A. J.
03/10/25
1 item of Media coverage
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Fox Chase, Moffitt Cancer Center experts collaborate on melanoma guideline review
Farma, J. M. & Olszanski, A. J.
02/12/25
1 item of Media coverage
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Fox Chase Cancer Center Researchers Review Guidelines for Therapies Given to Melanoma Patients Before and After Initial Treatment
Farma, J. M. & Olszanski, A. J.
02/11/25
1 item of Media coverage
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310 Temple Health Physicians Named 'Top Doctors' by Philadelphia Magazine
Mantia-Smaldone, G. M., Vijayvergia, N., Borghaei, H., Weiss, S. E., Bodor, J. N., Kumar, R., Berman, A. T., Khanal, R., Flieder, D. B., Chen, D. Y., Plimack, E. R., Dotan, E., Manley, C. J., Hernandez, E., Nejati, R. M., Ehya, H., Kutikov, A., Rubin, S. C., Hallman, M. A., Uzzo, R. G., Patel, S. A., Viterbo, R., Curcillo, P. G., Bleicher, R., Reddy, S. S., Edelman, M., Nakhoda, S. K., Greco, S. H., Miyamoto, C. T., Bauman, J., von Mehren, M., Yu, J. Q., Chwistek, M., Williams, A. D., Jain, A., Meyer, J. E., Castellanos, J. A., Hall, M. J., Ahmad, D., Farma, J. M., Weinberg, D. S., Friedberg, J., Wasik, M. A., Zibelman, M. R., Messmer, M., Wang, Y. L., Geynisman, D., Astsaturov, I., Olszanski, A. J., Simhan, J., Friedlander, J. I., Cohn, J., Sterious, S., Galloway, T. J., Wei, S., Aphale, A., McShane, M. M., Kumar, S. S., Walchak, A., Giri, A. P. & Sharda, P.
05/22/24
1 item of Media coverage
Press/Media