Research output per year
Research output per year
Research output
- 23 Article
- 23 results
Search results
-
2023
Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities
Krais, J. J., Glass, D. J., Chudoba, I., Wang, Y., Feng, W., Simpson, D., Patel, P., Liu, Z., Neumann-Domer, R., Betsch, R. G., Bernhardy, A. J., Bradbury, A. M., Conger, J., Yueh, W. T., Nacson, J., Pomerantz, R. T., Gupta, G. P., Testa, J. R. & Johnson, N., Dec 2023, In: Nature Communications. 14, 1, p. 7714 7714.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
TET1 and TDG Suppress Inflammatory Response in Intestinal Tumorigenesis: Implications for Colorectal Tumors With the CpG Island Methylator Phenotype
Tricarico, R., Madzo, J., Scher, G., Cohen, M., Jelinek, J., Maegawa, S., Nagarathinam, R., Scher, C., Chang, W. C., Nicolas, E., Slifker, M., Zhou, Y., Devarajan, K., Cai, K. Q., Kwok, T., Nakajima, P., Xu, J., Mancuso, P., Doneddu, V. & Bagella, L. & 21 others, , May 2023, In: Gastroenterology. 164, 6, p. 921-936.e1Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
ThPOK is a critical multifaceted regulator of myeloid lineage development
Basu, J., Olsson, A., Ferchen, K., Titerina, E. K., Chetal, K., Nicolas, E., Czyzewicz, P., Levchenko, D., Ge, L., Hua, X., Grimes, H. L., Salomonis, N. & Kappes, D. J., Aug 2023, In: Nature Immunology. 24, 8, p. 1295-1307 13 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
2022
An autonomous TCR signal-sensing switch influences CD4/CD8 lineage choice in mice
Basu, J., Zha, J., Nicolas, E., Coulton, M., Czyzewicz, P., Hua, X., Ge, L. & Kappes, D. J., Dec 2022, In: Communications Biology. 5, 1, p. 84 84.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Tumors by Restricting Downstream Hedgehog and Wnt Signaling
Sementino, E., Kadariya, Y., Cheung, M., Menges, C. W., Tan, Y., Kukuyan, A. M., Shrestha, U., Karchugina, S., Cai, K. Q., Peri, S., Duncan, J. S., Chernoff, J. & Testa, J. R., May 2022, In: Molecular Cancer Research. 20, 5, p. 699-711 13 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Investigation of the causal etiology in a patient with T-B+NK+ immunodeficiency
Sertori, R., Lin, J. X., Martinez, E., Rana, S., Sharo, A., Kazemian, M., Sunderam, U., Andrake, M., Shinton, S., Truong, B., Dunbrack, R. M., Liu, C., Srinivasan, R., Brenner, S. E., Seroogy, C. M., Puck, J. M., Leonard, W. J. & Wiest, D. L., Jul 29 2022, In: Frontiers in Immunology. 13, p. 928252 928252.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Pla2g2a promotes innate Th2-type immunity lymphocytes to increase B1a cells
Shinton, S. A., Brill-Dashoff, J. & Hayakawa, K., Aug 1 2022, In: Scientific Reports. 12, 1, 14899.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
The ERK2-DBP domain opposes pathogenesis of a mouse JAK2V617F-driven myeloproliferative neoplasm
Zhang, Y., Truong, B., Fahl, S. P., Martinez, E., Cai, K. Q., Al-Saleem, E. D., Gong, Y., Liebermann, D. A., Soboloff, J., Dunbrack, R., Levine, R. L., Fletcher, S., Kappes, D., Sykes, S. M., Shapiro, P. & Wiest, D. L., Jul 28 2022, In: Blood. 140, 4, p. 359-373 15 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2021
Essential role of a ThPOK autoregulatory loop in the maintenance of mature CD4+ T cell identity and function
Basu, J., Reis, B. S., Peri, S., Zha, J., Hua, X., Ge, L., Ferchen, K., Nicolas, E., Czyzewicz, P., Cai, K. Q., Tan, Y., Fuxman Bass, J. I., Walhout, A. J. M., Grimes, H. L., Grivennikov, S. I., Mucida, D. & Kappes, D. J., Jul 2021, In: Nature Immunology. 22, 8, p. 969-982 14 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
RNF168-mediated localization of BARD1 recruits the BRCA1-PALB2 complex to DNA damage
Wang, Y., Patel, P., Basu, J., Bernhardy, A. J., Johnson, N. & Krais, J. J., Jul 18 2021, In: Nature Communications. 12, 1, p. 5016 5016.Research output: Contribution to journal › Article › peer-review
Open Access58 Scopus citations -
2020
BRCA1 Mutational Complementation Induces Synthetic Viability
Nacson, J., Di Marcantonio, D., Wang, Y., Bernhardy, A. J., Clausen, E., Hua, X., Cai, K. Q., Martinez, E., Feng, W., Callén, E., Wu, W., Gupta, G. P., Testa, J. R., Nussenzweig, A., Sykes, S. M. & Johnson, N., Jun 4 2020, In: Molecular Cell. 78, 5, p. 951-959.e6Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
BTN3A1 governs antitumor responses by coordinating αβ and γδ T cells
Payne, K. K., Mine, J. A., Biswas, S., Chaurio, R. A., Perales-Puchalt, A., Anadon, C. M., Costich, T. L., Harro, C. M., Walrath, J., Ming, Q., Tcyganov, E., Buras, A. L., Rigolizzo, K. E., Mandal, G., Lajoie, J., Ophir, M., Tchou, J., Marchion, D., Luca, V. C. & Bobrowicz, P. & 7 others, , Aug 21 2020, In: Science. 369, 6506, p. 942-949 8 p.Research output: Contribution to journal › Article › peer-review
133 Scopus citations -
EZH2 Inhibition Sensitizes CARM1-High, Homologous Recombination Proficient Ovarian Cancers to PARP Inhibition
Karakashev, S., Fukumoto, T., Zhao, B., Lin, J., Wu, S., Fatkhutdinov, N., Park, P. H., Semenova, G., Jean, S., Cadungog, M. G., Borowsky, M. E., Kossenkov, A. V., Liu, Q. & Zhang, R., 2020, In: Cancer Cell. 37, 2, p. 157-167 e6Research output: Contribution to journal › Article › peer-review
Open Access121 Scopus citations -
LRIT3 is Required for Nyctalopin Expression and Normal ON and OFF Pathway Signaling in the Retina
Hasan, N., Pangeni, G., Ray, T. A., Fransen, K. M., Noel, J., Borghuis, B. G., McCall, M. A. & Gregg, R. G., Jan 1 2020, In: eNeuro. 7, 1, ENEURO.0002-20.2020.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
Mouse models of neutropenia reveal progenitor-stage-specific defects
Muench, D. E., Olsson, A., Ferchen, K., Pham, G., Serafin, R. A., Chutipongtanate, S., Dwivedi, P., Song, B., Hay, S., Chetal, K., Trump-Durbin, L. R., Mookerjee-Basu, J., Zhang, K., Yu, J. C., Lutzko, C., Myers, K. C., Nazor, K. L., Greis, K. D., Kappes, D. J. & Way, S. S. & 2 others, , May 2020, In: Nature. 582, 7810, p. 109-114 6 p.Research output: Contribution to journal › Article › peer-review
Open Access99 Scopus citations -
2019
Crucial Role of Increased Arid3a at the Pre-B and Immature B Cell Stages for B1a Cell Generation
Hayakawa, K., Li, Y. S., Shinton, S. A., Bandi, S. R., Formica, A. M., Brill-Dashoff, J. & Hardy, R. R., Mar 15 2019, In: Frontiers in Immunology. 10, MAR, p. 457 457.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Functional Conservation of a Developmental Switch in Mammals since the Jurassic Age
Mookerjee-Basu, J., Hua, X., Ge, L., Nicolas, E., Li, Q., Czyzewicz, P., Zhongping, D., Peri, S., Fuxmanbass, J. I., Walhout, A. J. M. & Kappes, D. J., Jan 1 2019, In: Molecular Biology and Evolution. 36, 1, p. 39-53 15 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Inactivation of BAP1 cooperates with losses of NF2 and CDKN2A to drive the development of pleural malignant mesothelioma in conditional mouse models
Kukuyan, A. M., Sementino, E., Kadariya, Y., Menges, C. W., Cheung, M., Tan, Y., Cai, K. Q., Slifker, M. J., Peri, S., Klein-Szanto, A. J., Rauscher, F. J. & Testa, J. R., Aug 15 2019, In: Cancer Research. 79, 16, p. 4113-4123 11 p.Research output: Contribution to journal › Article › peer-review
Open Access54 Scopus citations -
Mechanistic basis for impaired ferroptosis in cells expressing the African-centric S47 variant of p53
Leu, J. I., Murphy, M. E. & George, D. L., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 17, p. 8390-8396 7 p.Research output: Contribution to journal › Article › peer-review
Open Access99 Scopus citations -
Pak2 as a Novel Therapeutic Target for Cardioprotective Endoplasmic Reticulum Stress Response
Binder, P., Wang, S., Radu, M., Zin, M., Collins, L., Khan, S., Li, Y., Sekeres, K., Humphreys, N., Swanton, E., Reid, A., Pu, F., Oceandy, D., Guan, K., Hille, S. S., Frey, N., Müller, O. J., Cartwright, E. J., Chernoff, J. & Wang, X. & 1 others, , Mar 1 2019, In: Circulation Research. 124, 5, p. 696-711 16 p.Research output: Contribution to journal › Article › peer-review
Open Access74 Scopus citations -
Thymine DNA glycosylase as a novel target for melanoma
Mancuso, P., Tricarico, R., Bhattacharjee, V., Cosentino, L., Kadariya, Y., Jelinek, J., Nicolas, E., Einarson, M., Beeharry, N., Devarajan, K., Katz, R. A., Dorjsuren, D. G., Sun, H., Simeonov, A., Giordano, A., Testa, J. R., Davidson, G., Davidson, I., Larue, L. & Sobol, R. W. & 2 others, , May 2019, In: Oncogene. 38, 19, p. 3710-3728 19 p.Research output: Contribution to journal › Article › peer-review
Open Access37 Scopus citations -
Treatment of Cystathionine β-Synthase Deficiency in Mice Using a Minicircle-Based Naked DNA Vector
Lee, H. O., Gallego-Villar, L., Grisch-Chan, H. M., Häberle, J., Thöny, B. & Kruger, W. D., Sep 2019, In: Human Gene Therapy. 30, 9, p. 1093-1100 8 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Tumor cells containing the African-Centric S47 variant of TP53 show increased Warburg metabolism
Barnoud, T., Parris, J. L. D. & Murphy, M. E., 2019, In: Oncotarget. 10, 11, p. 1217-1223 7 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations