Laboratory Animal Facility

2023

Analysis and therapeutic targeting of the EP300 and CREBBP acetyltransferases in anaplastic large cell lymphoma and Hodgkin lymphoma

Wei, W., Song, Z., Chiba, M., Wu, W., Jeong, S., Zhang, J. P., Kadin, M. E., Nakagawa, M. & Yang, Y., Jan 2023, In: Leukemia. 37, 2, p. 396-407 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Analysis and therapeutic targeting of the IL-1R pathway in anaplastic large cell lymphoma

Song, Z., Wu, W., Wei, W., Xiao, W., Lei, M., Cai, K. Q., Huang, D. W., Jeong, S., Zhang, J. P., Wang, H., Kadin, M. E., Waldmann, T. A., Staudt, L. M., Nakagawa, M. & Yang, Y., Oct 12 2023, In: Blood. 142, 15, p. 1297-1311 15 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

An in-vivo study of the combined therapeutic effects of pulsed non-thermal focused ultrasound and radiation for prostate cancer

Chen, X., Cvetkovic, D., Chen, L. & Ma, C. M., 2023, In: International Journal of Radiation Biology. 99, 11, p. 1716-1723 8 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Folic Acid Supplementation Promotes Hypomethylation in Both the Inflamed Colonic Mucosa and Colitis-Associated Dysplasia

Chang, W. C. L., Ghosh, J., Cooper, H. S., Vanderveer, L., Schultz, B., Zhou, Y., Harvey, K. N., Kaunga, E., Devarajan, K., Li, Y., Jelinek, J., Fragoso, M. F., Sapienza, C. & Clapper, M. L., Apr 27 2023, In: Cancers. 15, 11, 2949.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities

Krais, J. J., Glass, D. J., Chudoba, I., Wang, Y., Feng, W., Simpson, D., Patel, P., Liu, Z., Neumann-Domer, R., Betsch, R. G., Bernhardy, A. J., Bradbury, A. M., Conger, J., Yueh, W. T., Nacson, J., Pomerantz, R. T., Gupta, G. P., Testa, J. R. & Johnson, N., Dec 2023, In: Nature Communications. 14, 1, p. 7714 7714.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Interferon-gamma signaling promotes melanoma progression and metastasis

Zhou, B., Basu, J., Kazmi, H. R., Chitrala, K. N., Mo, X., Preston-Alp, S., Cai, K. Q., Kappes, D. & Zaidi, M. R., Jan 27 2023, In: Oncogene. 42, 5, p. 351-363 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Loss of Pkd1 limits susceptibility to colitis and colorectal cancer

Nikonova, A. S., Deneka, A. Y., Silva, F. N., Pirestani, S., Tricarico, R., Kiseleva, A., Zhou, Y., Nicolas, E., Flieder, D. B., Grivennikov, S. I. & Golemis, E. A., Jul 5 2023, In: Oncogenesis. 12, 1, p. 40 40.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

PDLIM3 supports hedgehog signaling in medulloblastoma by facilitating cilia formation

Zhang, J., Yang, Y., Li, X., Li, G., Mizukami, T., Liu, Y., Wang, Y., Xu, G., Roder, H., Zhang, L. & Yang, Z. J., May 2023, In: Cell Death and Differentiation. 30, 5, p. 1198-1210 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Phthalocyanine-Blue Nanoparticles for the Direct Visualization of Tumors with White Light Illumination

Clapper, M. L., Amirshaghaghi, A., Chang, W. C., Chhay, B., Bartolomeu, A. R., Cheng, Z. & Tsourkas, A., Jul 19 2023, In: ACS applied materials & interfaces. 15, 28, p. 33373-33381 9 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

TET1 and TDG Suppress Inflammatory Response in Intestinal Tumorigenesis: Implications for Colorectal Tumors With the CpG Island Methylator Phenotype

Tricarico, R., Madzo, J., Scher, G., Cohen, M., Jelinek, J., Maegawa, S., Nagarathinam, R., Scher, C., Chang, W. C., Nicolas, E., Slifker, M., Zhou, Y., Devarajan, K., Cai, K. Q., Kwok, T., Nakajima, P., Xu, J., Mancuso, P., Doneddu, V. & Bagella, L. & 21 others, Williams, R., Balachandran, S., Maskalenko, N., Campbell, K., Ma, X., Cañadas, I., Viana-Errasti, J., Moreno, V., Valle, L., Grivennikov, S., Peshkova, I., Kurilenko, N., Mazitova, A., Koltsova, E., Lee, H., Walsh, M., Duttweiler, R., Whetstine, J. R., Yen, T. J., Issa, J. P. & Bellacosa, A., May 2023, In: Gastroenterology. 164, 6, p. 921-936.e1

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

ThPOK is a critical multifaceted regulator of myeloid lineage development

Basu, J., Olsson, A., Ferchen, K., Titerina, E. K., Chetal, K., Nicolas, E., Czyzewicz, P., Levchenko, D., Ge, L., Hua, X., Grimes, H. L., Salomonis, N. & Kappes, D. J., Aug 2023, In: Nature Immunology. 24, 8, p. 1295-1307 13 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

2022

ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis

Zhang, T., Yin, C., Fedorov, A., Qiao, L., Bao, H., Beknazarov, N., Wang, S., Gautam, A., Williams, R. M., Crawford, J. C., Peri, S., Studitsky, V., Beg, A. A., Thomas, P. G., Walkley, C., Xu, Y., Poptsova, M., Herbert, A. & Balachandran, S., Jun 2022, In: Nature. 606, 7914, p. 594-602 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

293 Scopus citations

An autonomous TCR signal-sensing switch influences CD4/CD8 lineage choice in mice

Basu, J., Zha, J., Nicolas, E., Coulton, M., Czyzewicz, P., Hua, X., Ge, L. & Kappes, D. J., Dec 2022, In: Communications Biology. 5, 1, p. 84 84.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

BAP1 maintains HIF-dependent interferon beta induction to suppress tumor growth in clear cell renal cell carcinoma

Langbein, L. E., El Hajjar, R., He, S., Sementino, E., Zhong, Z., Jiang, W., Leiby, B. E., Li, L., Uzzo, R. G., Testa, J. R. & Yang, H., Oct 28 2022, In: Cancer Letters. 547, p. 215885 215885.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Correction to: Thymine DNA glycosylase as a novel target for melanoma

Mancuso, P., Tricarico, R., Bhattacharjee, V., Cosentino, L., Kadariya, Y., Jelinek, J., Nicolas, E., Einarson, M., Beeharry, N., Devarajan, K., Katz, R. A., Dorjsuren, D. G., Sun, H., Simeonov, A., Giordano, A., Testa, J. R., Davidson, G., Davidson, I., Larue, L. & Sobol, R. W. & 2 others, Yen, T. J. & Bellacosa, A., May 2022, In: Oncogene. 41, 23, p. 3300-3301 2 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Dysregulation of miR-1-3p: An Early Event in Colitis-Associated Dysplasia

Fragoso, M. F., Fernandez, G. J., Vanderveer, L., Cooper, H. S., Slifker, M. & Clapper, M. L., Sep 27 2022, In: International Journal of Molecular Sciences. 23, 21, 13024.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Effects of Pubertal Exposure to Butyl Benzyl Phthalate, Perfluorooctanoic Acid, and Zeranol on Mammary Gland Development and Tumorigenesis in Rats

Su, Y., Santucci-Pereira, J., Dang, N. M., Kanefsky, J., Rahulkannan, V., Hillegass, M., Joshi, S., Gurdogan, H., Chen, Z., Bessonneau, V., Rudel, R., Ser-Dolansky, J., Schneider, S. S. & Russo, J., Feb 1 2022, In: International Journal of Molecular Sciences. 23, 3, 1398.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Identification of New Regulators of Pancreatic Cancer Cell Sensitivity to Oxaliplatin and Cisplatin

Skripova, V., Vlasenkova, R., Zhou, Y., Astsaturov, I. & Kiyamova, R., Feb 1 2022, In: Molecules. 27, 4, 1289.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

IL27 Signaling Serves as an Immunologic Checkpoint for Innate Cytotoxic Cells to Promote Hepatocellular Carcinoma

Aghayev, T., Mazitova, A. M., Fang, J. R., Peshkova, I. O., Rausch, M., Hung, M., White, K. F., Masia, R., Titerina, E. K., Fatkhullina, A. R., Cousineau, I., Turcotte, S., Zhigarev, D., Marchenko, A., Khoziainova, S., Makhov, P., Tan, Y. F., Kossenkov, A. V., Wiest, D. L. & Stagg, J. & 7 others, Wang, X. W., Campbell, K. S., Dzutsev, A. K., Trinchieri, G., Hill, J. A., Grivennikov, S. I. & Koltsova, E. K., Aug 1 2022, In: Cancer Discovery. 12, 8, p. 1960-1983 24 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Tumors by Restricting Downstream Hedgehog and Wnt Signaling

Sementino, E., Kadariya, Y., Cheung, M., Menges, C. W., Tan, Y., Kukuyan, A. M., Shrestha, U., Karchugina, S., Cai, K. Q., Peri, S., Duncan, J. S., Chernoff, J. & Testa, J. R., May 2022, In: Molecular Cancer Research. 20, 5, p. 699-711 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Inflammation as a chemoprevention target in asbestos-induced malignant mesothelioma

Kadariya, Y., Sementino, E., Shrestha, U., Gorman, G., White, J. M., Ross, E. A., Clapper, M. L., Neamati, N., Miller, M. S. & Testa, J. R., Dec 1 2022, In: Carcinogenesis. 43, 12, p. 1137-1148 12 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Investigation of the causal etiology in a patient with T-B+NK+ immunodeficiency

Sertori, R., Lin, J. X., Martinez, E., Rana, S., Sharo, A., Kazemian, M., Sunderam, U., Andrake, M., Shinton, S., Truong, B., Dunbrack, R. M., Liu, C., Srinivasan, R., Brenner, S. E., Seroogy, C. M., Puck, J. M., Leonard, W. J. & Wiest, D. L., Jul 29 2022, In: Frontiers in Immunology. 13, p. 928252 928252.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Loss of Ribosomal Protein Paralog Rpl22-like1 Blocks Lymphoid Development without Affecting Protein Synthesis

Fahl, S. P., Sertori, R., Zhang, Y., Contreras, A. V., Harris, B., Wang, M., Perrigoue, J., Balachandran, S., Kennedy, B. K. & Wiest, D. L., Feb 15 2022, In: Journal of Immunology. 208, 4, p. 870-880 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Mesothelioma Mouse Models with Mixed Genomic States of Chromosome and Microsatellite Instability

Song, Y., Baxter, S. S., Dai, L., Sanders, C., Burkett, S., Baugher, R. N., Mellott, S. D., Young, T. B., Lawhorn, H. E., Difilippantonio, S., Karim, B., Kadariya, Y., Pinto, L. A., Testa, J. R. & Shoemaker, R. H., May 24 2022, In: Cancers. 14, 13, 3108.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

NEDD9 sustains hexokinase expression to promote glycolysis

Deneka, A. Y., Nikonova, A. S., Lee, H. O., Kruger, W. D. & Golemis, E. A., Apr 11 2022, In: Oncogenesis. 11, 1, p. 15 15.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Ovarian Cancers with Low CIP2A Tumor Expression Constitute an APR-246-Sensitive Disease Subtype

Cvrljevic, A. N., Butt, U., Huhtinen, K., Grönroos, T. J., Böckelman, C., Lassus, H., Butzow, R., Haglund, C., Kaipio, K., Arsiola, T., Laajala, T. D., Connolly, D. C., Ristimäki, A., Carpen, O., Pouwels, J. & Westermarck, J., Jul 2022, In: Molecular Cancer Therapeutics. 21, 7, p. 1236-1245 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Suppression of Ca²⁺ signaling enhances melanoma progression

Gross, S., Hooper, R., Tomar, D., Armstead, A. P., Shanas, N., Mallu, P., Joshi, H., Ray, S., Chong, P. L. G., Astsaturov, I., Farma, J. M., Cai, K. Q., Chitrala, K. N., Elrod, J. W., Zaidi, M. R. & Soboloff, J., Sep 4 2022, In: EMBO Journal. 41, 19, p. e110046 e110046.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma

Capparelli, C., Purwin, T. J., Glasheen, M. K., Caksa, S., Tiago, M., Wilski, N., Pomante, D., Rosenbaum, S., Nguyen, M. Q., Cai, W., Franco-Barraza, J., Zheng, R., Kumar, G., Chervoneva, I., Shimada, A., Rebecca, V. W., Snook, A. E., Hookim, K., Xu, X. & Cukierman, E. & 2 others, Herlyn, M. & Aplin, A. E., Feb 16 2022, In: Nature Communications. 13, 1, p. 1381 1381.

Research output: Contribution to journal › Article › peer-review

Open Access

55 Scopus citations

The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells

Kurimchak, A. M., Herrera-Montávez, C., Montserrat-Sangrà, S., Araiza-Olivera, D., Hu, J., Neumann-Domer, R., Kuruvilla, M., Bellacosa, A., Testa, J. R., Jin, J. & Duncan, J. S., Aug 30 2022, In: Science Signaling. 15, 749, p. eabn2707 eabn2707.

Research output: Contribution to journal › Article › peer-review

Open Access

67 Scopus citations

The ERK2-DBP domain opposes pathogenesis of a mouse JAK2V617F-driven myeloproliferative neoplasm

Zhang, Y., Truong, B., Fahl, S. P., Martinez, E., Cai, K. Q., Al-Saleem, E. D., Gong, Y., Liebermann, D. A., Soboloff, J., Dunbrack, R., Levine, R. L., Fletcher, S., Kappes, D., Sykes, S. M., Shapiro, P. & Wiest, D. L., Jul 28 2022, In: Blood. 140, 4, p. 359-373 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

ZBP1 promotes inflammatory responses downstream of TLR3/TLR4 via timely delivery of RIPK1 to TRIF

Muendlein, H. I., Connolly, W. M., Magri, Z., Jetton, D., Smirnova, I., Degterev, A., Balachandran, S. & Poltorak, A., Jun 14 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 24, p. e2113872119 e2113872119.

Research output: Contribution to journal › Article › peer-review

Open Access

60 Scopus citations

2021

Analysis of differential neonatal lethality in cystathionine β-synthase deficient mouse models using metabolic profiling

Kruger, W. D., Gupta, S., Wang, L., Slifker, M. J., Cai, K., Maclean, K. N., Wasek, B. & Bottiglieri, T., May 2021, In: FASEB Journal. 35, 6, p. e21629 e21629.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

A Novel Germline Heterozygous BCL11B Variant Causing Severe Atopic Disease and Immune Dysregulation

Lu, H. Y., Sertori, R., Contreras, A. V., Hamer, M., Messing, M., Del Bel, K. L., Lopez-Rangel, E., Chan, E. S., Rehmus, W., Milner, J. D., McNagny, K. M., Lehman, A. & Turvey, S. E., Nov 23 2021, In: Frontiers in Immunology. 12, p. 788278 788278.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

A novel model of alternative NF-κB pathway activation in anaplastic large cell lymphoma

Wang, H., Wei, W., Zhang, J. P., Song, Z., Li, Y., Xiao, W., Liu, Y., Zeng, M. S., Petrus, M. N., Thomas, C. J., Kadin, M. E., Nakagawa, M., Waldmann, T. A. & Yang, Y., Jul 2021, In: Leukemia. 35, 7, p. 1976-1989 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Combined inhibition of AKT and KIT restores expression of programmed cell death 4 (PDCD4) in gastrointestinal stromal tumor

Kozinova, M., Joshi, S., Ye, S., Belinsky, M. G., Sharipova, D., Farma, J. M., Reddy, S. S., Litwin, S., Devarajan, K., Campos, A. R., Yu, Y., Schwartz, B., von Mehren, M. & Rink, L., Jun 23 2021, In: Cancers. 13, 15, 3699.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

CRY1-CBS binding regulates circadian clock function and metabolism

Kruger, W. D., Cal-Kayitmazbatir, S., Kulkoyluoglu-Cotul, E., Growe, J., Selby, C. P., Rhoades, S. D., Malik, D., Oner, H., Asimgil, H., Francey, L. J., Sancar, A., Hogenesch, J. B., Weljie, A., Anafi, R. C. & Kavakli, I. H., Jan 2021, In: FEBS Journal. 288, 2, p. 614-639 26 p.

Research output: Contribution to journal › Article › peer-review

Open Access

36 Scopus citations

Essential role of a ThPOK autoregulatory loop in the maintenance of mature CD4⁺ T cell identity and function

Basu, J., Reis, B. S., Peri, S., Zha, J., Hua, X., Ge, L., Ferchen, K., Nicolas, E., Czyzewicz, P., Cai, K. Q., Tan, Y., Fuxman Bass, J. I., Walhout, A. J. M., Grimes, H. L., Grivennikov, S. I., Mucida, D. & Kappes, D. J., Jul 2021, In: Nature Immunology. 22, 8, p. 969-982 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Evaluation of the small-molecule BRD4 degrader CFT-2718 in small-cell lung cancer and pancreatic cancer models

Golemis, E. A., Sun, D., Nikonova, A. S., Zhang, P., Deneka, A. Y., Fitzgerald, M. E., Michael, R. E., Lee, L., Lilly, A. C., Fisher, S. L., Phillips, A. J., Nasveschuk, C. G., Proia, D. A. & Tu, Z., Aug 2021, In: Molecular Cancer Therapeutics. 20, 8, p. 1367-1377 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Identification of Wee1 as a target in combination with avapritinib for gastrointestinal stromal tumor treatment

Ye, S., Sharipova, D., Kozinova, M., Klug, L., D’Souza, J., Belinsky, M. G., Johnson, K. J., Einarson, M. B., Devarajan, K., Zhou, Y., Litwin, S., Heinrich, M. C., DeMatteo, R., von Mehren, M., Duncan, J. S. & Rink, L., Dec 25 2021, In: JCI insight. 6, 2, e143474.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Long-term functional correction of cystathionine β-synthase deficiency in mice by adeno-associated viral gene therapy

Kruger, W. D., Lee, H.-O., Salami, C. O., Kaminsky, S. M. & Crystal, R. G., Nov 2021, In: Journal of Inherited Metabolic Disease. 44, 6, p. 1382-1392 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Musashi-2 (MSI2) regulates epidermal growth factor receptor (EGFR) expression and response to EGFR inhibitors in EGFR-mutated non-small cell lung cancer (NSCLC)

Makhov, P., Bychkov, I., Faezov, B., Deneka, A. Y., Kudinov, A. E., Nicolas, E., Brebion, R., Avril, E., Cai, K., Kharin, L. V., Voloshin, M., Frantsiyants, E., Karnaukhov, N., Kit, O. I., Topchu, I., Fazliyeva, R., Nikonova, A. S., Serebriiskii, I. G., Borghaei, H. & Edelman, M. & 3 others, Dulaimi, E., Golemis, E. A. & Boumber, Y., Mar 15 2021, In: Oncogenesis. 10, 3, p. 29 29.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Nedd9 restrains autophagy to limit growth of early stage non-small cell lung cancer

Deneka, A. Y., Kopp, M. C., Nikonova, A. S., Gaponova, A. V., Kiseleva, A. A., Hensley, H. H., Flieder, D. B., Serebriiskii, I. G. & Golemis, E. A., Jul 1 2021, In: Cancer Research. 81, 13, p. 3717-3726 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Nestin is required for spindle assembly and cell cycle progression in glioblastoma cells

Wang, Q., Wu, H., Hu, J., Fu, H., Qu, Y., Yang, Y., Cai, Q., Efimov, A., Wu, M., Yen, T., Wang, Y. & Yang, Z. J., Oct 2021, In: Molecular Cancer Research. 19, 10, p. 1651-1665 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Netrin G1 promotes pancreatic tumorigenesis through cancer-associated fibroblast–driven nutritional support and immunosuppression

Francescone, R., Vendramini-Costa, D. B., Franco-Barraza, J., Wagner, J., Muir, A., Lau, A. N., Gabitova, L., Pazina, T., Gupta, S., Luong, T., Rollins, D., Malik, R., Thapa, R. J., Restifo, D., Zhou, Y., Cai, K. Q., Hensley, H. H., Tan, Y., Kruger, W. D. & Devarajan, K. & 9 others, Balachandran, S., Klein-Szanto, A. J., Wang, H., El-Deiry, W. S., Vander Heiden, M. G., Peri, S., Campbell, K. S., Astsaturov, I. & Cukierman, E., 2021, In: Cancer Discovery. 11, 2, p. 446-479 34 p.

Research output: Contribution to journal › Article › peer-review

Open Access

148 Scopus citations

Noncanonical Transmission of a Measles Virus Vaccine Strain from Neurons to Astrocytes

Poelaert, K. C. K., Williams, R. M., Matullo, C. M. & Rall, G. F., 2021, In: Mbio. 12, 2, e00288-21.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Novel protein‐based vaccine against self‐antigen reduces the formation of sporadic colon adenomas in mice

Belnoue, E., Leystra, A. A., Carboni, S., Cooper, H. S., Macedo, R. T., Harvey, K. N., Colby, K. B., Campbell, K. S., Vanderveer, L. A., Clapper, M. L. & Derouazi, M., Feb 2021, In: Cancers. 13, 4, p. 1-16 16 p., 845.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

Platelet microRNAs inhibit primary tumor growth via broad modulation of tumor cell mRNA expression in ectopic pancreatic cancer in mice

Wurtzel, J. G. T., Lazar, S., Sikder, S., Cai, K. Q., Astsaturov, I., Weyrich, A. S., Rowley, J. W. & Goldfinger, L. E., Dec 2021, In: PLoS ONE. 16, 12 December, p. e0261633 e0261633.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Preparation of mouse pancreatic tumor for single-cell RNA sequencing and analysis of the data

Surumbayeva, A., Kotliar, M., Gabitova-Cornell, L., Kartashov, A., Peri, S., Salomonis, N., Barski, A. & Astsaturov, I., Dec 17 2021, In: STAR Protocols. 2, 4, p. 100989 100989.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Purification of differentiated tumor cells from medulloblastoma for transplantation into mouse cerebellum

Yang, Y., Qu, Y., Cheng, Y., Guo, D., Fan, Q. & Yang, Z. J., Jun 18 2021, In: STAR Protocols. 2, 2, p. 100409 100409.

Research output: Contribution to journal › Article › peer-review

Open Access

Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency

Johnson, N., Cong, K., Peng, M., Kousholt, A. N., Lee, W. T. C., Lee, S., Nayak, S. U., Krais, J. J., VanderVere-Carozza, P. S., Pawelczak, K. S., Calvo, J. A., Panzarino, N. J., Turchi, J. J., Jonkers, J., Rothenberg, E. & Cantor, S. B., Aug 5 2021, In: Molecular Cell. 81, 15, p. 3128-3144.e7

Research output: Contribution to journal › Article › peer-review

Open Access

219 Scopus citations

Laboratory Animal Facility

Research output

Search results