Cell Culture Facility

2023

A CRISPR-based system to investigate HBV cccDNA biology

Seeger, C., Oct 2023, In: Journal of Virology. 97, 10

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Analysis and therapeutic targeting of the EP300 and CREBBP acetyltransferases in anaplastic large cell lymphoma and Hodgkin lymphoma

Wei, W., Song, Z., Chiba, M., Wu, W., Jeong, S., Zhang, J. P., Kadin, M. E., Nakagawa, M. & Yang, Y., Jan 2023, In: Leukemia. 37, 2, p. 396-407 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

Analysis and therapeutic targeting of the IL-1R pathway in anaplastic large cell lymphoma

Song, Z., Wu, W., Wei, W., Xiao, W., Lei, M., Cai, K. Q., Huang, D. W., Jeong, S., Zhang, J. P., Wang, H., Kadin, M. E., Waldmann, T. A., Staudt, L. M., Nakagawa, M. & Yang, Y., Oct 12 2023, In: Blood. 142, 15, p. 1297-1311 15 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy

Jang, H. J., Hostetter, G., MacFarlane, A. W., Madaj, Z., Ross, E. A., Hinoue, T., Kulchycki, J. R., Burgos, R. S., Tafseer, M., Alpaugh, R. K., Schwebel, C. L., Kokate, R., Geynisman, D. M., Zibelman, M. R., Ghatalia, P., Nichols, P. W., Chung, W., Madzo, J., Hahn, N. & Quinn, D. I. & 7 others, Issa, J. P., Topper, M., Baylin, S. B., Shen, H., Campbell, K. S., Jones, P. A. & Plimack, E. R., Jun 1 2023, In: Clinical Cancer Research. 29, 11, p. 2052-2065 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Scopus citations

Candidate variants in DNA replication and repair genes in early-onset renal cell carcinoma patients referred for germline testing

Demidova, E. V., Serebriiskii, I. G., Vlasenkova, R., Kelow, S., Andrake, M. D., Hartman, T. R., Kent, T., Virtucio, J., Rosen, G. L., Pomerantz, R. T., Dunbrack, R. L., Golemis, E. A., Hall, M. J., Chen, D. Y. T., Daly, M. B. & Arora, S., Mar 24 2023, In: Bmc Genomics. 24, 1, p. 212 212.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

CD30 Regulation of IL-13-STAT6 Pathway in Breast Implant-Associated Anaplastic Large Cell Lymphoma

Kadin, M. E., Morgan, J., Wei, W., Song, Z. & Yang, Y., Feb 1 2023, In: Aesthetic Surgery Journal. 43, 2, p. 137-146 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Epigenetic balance ensures mechanistic control of MLL amplification and rearrangement

Gray, Z. H., Chakraborty, D., Duttweiler, R. R., Alekbaeva, G. D., Murphy, S. E., Chetal, K., Ji, F., Ferman, B. I., Honer, M. A., Wang, Z., Myers, C., Sun, R., Kaniskan, H. Ü., Toma, M. M., Bondarenko, E. A., Santoro, J. N., Miranda, C., Dillingham, M. E., Tang, R. & Gozani, O. & 6 others, Jin, J., Skorski, T., Duy, C., Lee, H., Sadreyev, R. I. & Whetstine, J. R., Oct 12 2023, In: Cell. 186, 21, p. 4528-4545.e18

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

FAM122A ensures cell cycle interphase progression and checkpoint control as a SLiM-dependent substrate-competitive inhibitor to the B55⍺/PP2A phosphatase

Wasserman, J. S., Faezov, B., Patel, K. R., Kurimchak, A. N., Palacio, S. M., Fowle, H., McEwan, B. C., Xu, Q., Zhao, Z., Cressey, L., Johnson, N., Duncan, J. S., Kettenbach, A. N., Dunbrack, R. L. & Grana, X., 2023, (bioRxiv : the preprint server for biology).

Research output: Working paper › Preprint

Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities

Krais, J. J., Glass, D. J., Chudoba, I., Wang, Y., Feng, W., Simpson, D., Patel, P., Liu, Z., Neumann-Domer, R., Betsch, R. G., Bernhardy, A. J., Bradbury, A. M., Conger, J., Yueh, W. T., Nacson, J., Pomerantz, R. T., Gupta, G. P., Testa, J. R. & Johnson, N., Dec 2023, In: Nature Communications. 14, 1, 7714.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Inhibition of talin-induced integrin activation by a double-hit stapled peptide

Gao, T., Cho, E. A., Zhang, P. & Wu, J., Aug 3 2023, In: Structure. 31, 8, p. 948-957.e3

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Interferon-gamma signaling promotes melanoma progression and metastasis

Zhou, B., Basu, J., Kazmi, H. R., Chitrala, K. N., Mo, X., Preston-Alp, S., Cai, K. Q., Kappes, D. & Zaidi, M. R., Jan 27 2023, In: Oncogene. 42, 5, p. 351-363 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

Kinome profiling identifies MARK3 and STK10 as potential therapeutic targets in uveal melanoma

Baqai, U., Kurimchak, A. M., Trachtenberg, I. V., Purwin, T. J., Haj, J. I., Han, A., Luo, K., Pachon, N. F., Jeon, A., Chua, V., Davies, M. A., Gutkind, J. S., Benovic, J. L., Duncan, J. S. & Aplin, A. E., Dec 2023, In: Journal of Biological Chemistry. 299, 12, 105418.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Loss of Pkd1 limits susceptibility to colitis and colorectal cancer

Nikonova, A. S., Deneka, A. Y., Silva, F. N., Pirestani, S., Tricarico, R., Kiseleva, A., Zhou, Y., Nicolas, E., Flieder, D. B., Grivennikov, S. I. & Golemis, E. A., Jul 5 2023, In: Oncogenesis. 12, 1, p. 40 40.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

PDLIM3 supports hedgehog signaling in medulloblastoma by facilitating cilia formation

Zhang, J., Yang, Y., Li, X., Li, G., Mizukami, T., Liu, Y., Wang, Y., Xu, G., Roder, H., Zhang, L. & Yang, Z. J., May 2023, In: Cell Death and Differentiation. 30, 5, p. 1198-1210 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Regulation of VEGFR2 and AKT Signaling by Musashi-2 in Lung Cancer

Bychkov, I., Topchu, I., Makhov, P., Kudinov, A., Patel, J. D. & Boumber, Y., Mar 28 2023, In: Cancers. 15, 9, 2529.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

SHP1 loss augments DLBCL cellular response to ibrutinib: a candidate predictive biomarker

Wu, W., Lu, P., Patel, P., Ma, J., Cai, K. Q., Mallikarjuna, V. S., Poureghbali, S., Nakhoda, S. R., Nejati, R. & Lynn Wang, Y., Feb 3 2023, In: Oncogene. 42, 6, p. 409-420 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

TET1 and TDG Suppress Inflammatory Response in Intestinal Tumorigenesis: Implications for Colorectal Tumors With the CpG Island Methylator Phenotype

Tricarico, R., Madzo, J., Scher, G., Cohen, M., Jelinek, J., Maegawa, S., Nagarathinam, R., Scher, C., Chang, W. C., Nicolas, E., Slifker, M., Zhou, Y., Devarajan, K., Cai, K. Q., Kwok, T., Nakajima, P., Xu, J., Mancuso, P., Doneddu, V. & Bagella, L. & 21 others, Williams, R., Balachandran, S., Maskalenko, N., Campbell, K., Ma, X., Cañadas, I., Viana-Errasti, J., Moreno, V., Valle, L., Grivennikov, S., Peshkova, I., Kurilenko, N., Mazitova, A., Koltsova, E., Lee, H., Walsh, M., Duttweiler, R., Whetstine, J. R., Yen, T. J., Issa, J. P. & Bellacosa, A., May 2023, In: Gastroenterology. 164, 6, p. 921-936.e1

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

The RNA-binding motif protein 14 regulates telomere integrity at the interface of TERRA and telomeric R-loops

Wang, Y., Zhu, W., Jang, Y., Sommers, J. A., Yi, G., Puligilla, C., Croteau, D. L., Yang, Y., Kai, M. & Liu, Y., Dec 11 2023, In: Nucleic Acids Research. 51, 22, p. 12242-12260 19 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

The telomerase reverse transcriptase elongates reversed replication forks at telomeric repeats

Huda, A., Arakawa, H., Mazzucco, G., Galli, M., Petrocelli, V., Casola, S., Chen, L. & Doksani, Y., Mar 2023, In: Science advances. 9, 12, p. eadf2011 eadf2011.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Trogocytosis of cancer-associated fibroblasts promotes pancreatic cancer growth and immune suppression via phospholipid scramblase anoctamin 6 (ANO6)

Ogier, C., Solomon, A. M. C., Lu, Z., Recoules, L., Klochkova, A., Gabitova-Cornell, L., Bayarmagnai, B., Restifo, D., Surumbayeva, A., Vendramini-Costa, D. B., Deneka, A. Y., Francescone, R., Lilly, A. C., Sipman, A., Gardiner, J. C., Luong, T., Franco-Barraza, J., Ibeme, N., Cai, K. Q. & Einarson, M. B. & 13 others, Nicolas, E., Efimov, A., Megill, E., Snyder, N. W., Bousquet, C., Cros, J., Zhou, Y., Golemis, E. A., Gligorijevic, B., Soboloff, J., Fuchs, S. Y., Cukierman, E. & Astsaturov, I., 2023, (bioRxiv : the preprint server for biology).

Research output: Working paper › Preprint

Tumor-Suppressive and Immune-Stimulating Roles of Cholesterol 25-hydroxylase in Pancreatic Cancer Cells

McBrearty, N., Cho, C., Chen, J., Zahedi, F., Peck, A. R., Radaelli, E., Assenmacher, C. A., Pavlak, C., Devine, A., Yu, P., Lu, Z., Zhang, H., Li, J., Pitarresi, J. R., Astsaturov, I., Cukierman, E., Rustgi, A. K., Stanger, B. Z., Rui, H. & Fuchs, S. Y., Mar 1 2023, In: Molecular Cancer Research. 21, 3, p. 228-239 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

2022

ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis

Zhang, T., Yin, C., Fedorov, A., Qiao, L., Bao, H., Beknazarov, N., Wang, S., Gautam, A., Williams, R. M., Crawford, J. C., Peri, S., Studitsky, V., Beg, A. A., Thomas, P. G., Walkley, C., Xu, Y., Poptsova, M., Herbert, A. & Balachandran, S., Jun 2022, In: Nature. 606, 7914, p. 594-602 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

334 Scopus citations

Clinical Validation of an Alternative Specimen Collection Kit for SARS-CoV-2 Testing at Fox Chase Cancer Center

Baldwin, D. A., Gigli, C. R., Kwok, T., Connelly, S., Helstrom, J. L., Ebersole, B., Ross, E. A., Araten, M., Glickman, J., Glickman, R. & Horwitz, E. M., Sep 15 2022, In: Journal of Biomolecular Techniques. 33, 3, 3fc1f5fe.2008dbc6.

Research output: Contribution to journal › Article › peer-review

Open Access

Dysregulation of miR-1-3p: An Early Event in Colitis-Associated Dysplasia

Fragoso, M. F., Fernandez, G. J., Vanderveer, L., Cooper, H. S., Slifker, M. & Clapper, M. L., Sep 27 2022, In: International Journal of Molecular Sciences. 23, 21, 13024.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Eribulin normalizes pancreatic cancer-associated fibroblasts by simulating selected features of TGFβ inhibition

Luong, T. & Cukierman, E., Dec 2022, In: Bmc Cancer. 22, 1, p. 1255 1255.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Expanding the prostate cancer cell line repertoire with ACRJ-PC28, an AR-negative neuroendocrine cell line derived from an African-Caribbean patient

Valentine, H., Aiken, W., Morrison, B., Zhao, Z., Fowle, H., Wasserman, J. S., Thompson, E., Chin, W., Young, M., Clarke, S., Gibbs, D., Harrison, S., McLaughlin, W., Kwok, T., Jin, F., Campbell, K. S., Horvath, A., Thompson, R., Lee, N. H. & Zhou, Y. & 3 others, Graña, X., Ragin, C. & Badal, S., Nov 2022, In: Cancer Res Commun. 2, 11, p. 1355-1371 17 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Genome-wide CRISPR screens identify CD48 defining susceptibility to NK cytotoxicity in peripheral T-cell lymphomas

Chiba, M., Shimono, J., Ishio, T., Takei, N., Kasahara, K., Ogasawara, R., Ara, T., Goto, H., Izumiyama, K., Otsuguro, S., Perera, L. P., Hasegawa, H., Maeda, M., Hashino, S., Maenaka, K., Teshima, T., Waldmann, T. A., Yang, Y. & Nakagawa, M., Nov 3 2022, In: Blood. 140, 18, p. 1951-1963 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

IL27 Signaling Serves as an Immunologic Checkpoint for Innate Cytotoxic Cells to Promote Hepatocellular Carcinoma

Aghayev, T., Mazitova, A. M., Fang, J. R., Peshkova, I. O., Rausch, M., Hung, M., White, K. F., Masia, R., Titerina, E. K., Fatkhullina, A. R., Cousineau, I., Turcotte, S., Zhigarev, D., Marchenko, A., Khoziainova, S., Makhov, P., Tan, Y. F., Kossenkov, A. V., Wiest, D. L. & Stagg, J. & 7 others, Wang, X. W., Campbell, K. S., Dzutsev, A. K., Trinchieri, G., Hill, J. A., Grivennikov, S. I. & Koltsova, E. K., Aug 1 2022, In: Cancer Discovery. 12, 8, p. 1960-1983 24 p.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Tumors by Restricting Downstream Hedgehog and Wnt Signaling

Sementino, E., Kadariya, Y., Cheung, M., Menges, C. W., Tan, Y., Kukuyan, A. M., Shrestha, U., Karchugina, S., Cai, K. Q., Peri, S., Duncan, J. S., Chernoff, J. & Testa, J. R., May 2022, In: Molecular Cancer Research. 20, 5, p. 699-711 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Inflammation as a chemoprevention target in asbestos-induced malignant mesothelioma

Kadariya, Y., Sementino, E., Shrestha, U., Gorman, G., White, J. M., Ross, E. A., Clapper, M. L., Neamati, N., Miller, M. S. & Testa, J. R., Dec 1 2022, In: Carcinogenesis. 43, 12, p. 1137-1148 12 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Interferon-gamma induces melanogenesis via post-translational regulation of tyrosinase

Mo, X., Kazmi, H. R., Preston-Alp, S., Zhou, B. & Zaidi, M. R., May 2022, In: Pigment Cell and Melanoma Research. 35, 3, p. 342-355 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Loss of Ribosomal Protein Paralog Rpl22-like1 Blocks Lymphoid Development without Affecting Protein Synthesis

Fahl, S. P., Sertori, R., Zhang, Y., Contreras, A. V., Harris, B., Wang, M., Perrigoue, J., Balachandran, S., Kennedy, B. K. & Wiest, D. L., Feb 15 2022, In: Journal of Immunology. 208, 4, p. 870-880 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Lymphocyte Exhaustion in AML Patients and Impacts of HMA/Venetoclax or Intensive Chemotherapy on Their Biology

Zhigarev, D., Varshavsky, A., MacFarlane, A. W., Jayaguru, P., Barreyro, L., Khoreva, M., Dulaimi, E., Nejati, R., Drenberg, C. & Campbell, K. S., Jun 10 2022, In: Cancers. 14, 14, 3352.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Mesothelioma Mouse Models with Mixed Genomic States of Chromosome and Microsatellite Instability

Song, Y., Baxter, S. S., Dai, L., Sanders, C., Burkett, S., Baugher, R. N., Mellott, S. D., Young, T. B., Lawhorn, H. E., Difilippantonio, S., Karim, B., Kadariya, Y., Pinto, L. A., Testa, J. R. & Shoemaker, R. H., May 24 2022, In: Cancers. 14, 13, 3108.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

NEDD9 sustains hexokinase expression to promote glycolysis

Deneka, A. Y., Nikonova, A. S., Lee, H. O., Kruger, W. D. & Golemis, E. A., Apr 11 2022, In: Oncogenesis. 11, 1, p. 15 15.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

NetrinG1+ Cancer-Associated Fibroblasts Generate Unique Extracellular Vesicles that Support the Survival of Pancreatic Cancer Cells Under Nutritional Stress

Raghavan, K., Francescone, R., Franco-Barraza, J., Gardiner, J. C., Vendramini-Costa, D., Luong, T., Pourmandi, N., Andren, A., Kurimchak, A., Ogier, C., Campbell, P., Duncan, J., Lyssiotis, C., Languino, L. & Cukierman, E., Sep 2022, p. 1017-1036. 20 p.

Research output: Contribution to conference › Paper › peer-review

30 Scopus citations

Personalized genome assembly for accurate cancer somatic mutation discovery using tumor-normal paired reference samples

Xiao, C., Chen, Z., Chen, W., Padilla, C., Colgan, M., Wu, W., Fang, L. T., Liu, T., Yang, Y., Schneider, V., Wang, C. & Xiao, W., Dec 2022, In: Genome Biology. 23, 1, 237.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma

Capparelli, C., Purwin, T. J., Glasheen, M. K., Caksa, S., Tiago, M., Wilski, N., Pomante, D., Rosenbaum, S., Nguyen, M. Q., Cai, W., Franco-Barraza, J., Zheng, R., Kumar, G., Chervoneva, I., Shimada, A., Rebecca, V. W., Snook, A. E., Hookim, K., Xu, X. & Cukierman, E. & 2 others, Herlyn, M. & Aplin, A. E., Dec 2022, In: Nature Communications. 13, 1, 1381.

Research output: Contribution to journal › Article › peer-review

Open Access

64 Scopus citations

TGS1 impacts snRNA 3^'-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration

Chen, L., Roake, C. M., Maccallini, P., Bavasso, F., Dehghannasiri, R., Santonicola, P., Mendoza-Ferreira, N., Scatolini, L., Rizzuti, L., Esposito, A., Gallotta, I., Francia, S., Cacchione, S., Galati, A., Palumbo, V., Kobin, M. A., Tartaglia, G. G., Colantoni, A., Proietti, G. & Wu, Y. & 10 others, Hammerschmidt, M., De Pittà, C., Sales, G., Salzman, J., Pellizzoni, L., Wirth, B., Di Schiavi, E., Gatti, M., Artandi, S. E. & Raffa, G. D., Nov 28 2022, In: Nucleic Acids Research. 50, 21, p. 12400-12424 25 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells

Kurimchak, A. M., Herrera-Montávez, C., Montserrat-Sangrà, S., Araiza-Olivera, D., Hu, J., Neumann-Domer, R., Kuruvilla, M., Bellacosa, A., Testa, J. R., Jin, J. & Duncan, J. S., Aug 30 2022, In: Science Signaling. 15, 749, p. eabn2707 eabn2707.

Research output: Contribution to journal › Article › peer-review

Open Access

84 Scopus citations

The ERK2-DBP domain opposes pathogenesis of a mouse JAK2V617F-driven myeloproliferative neoplasm

Zhang, Y., Truong, B., Fahl, S. P., Martinez, E., Cai, K. Q., Al-Saleem, E. D., Gong, Y., Liebermann, D. A., Soboloff, J., Dunbrack, R., Levine, R. L., Fletcher, S., Kappes, D., Sykes, S. M., Shapiro, P. & Wiest, D. L., Jul 28 2022, In: Blood. 140, 4, p. 359-373 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

The S-adenosylmethionine analog sinefungin inhibits the trimethylguanosine synthase TGS1 to promote telomerase activity and telomere lengthening

Galati, A., Scatolini, L., Micheli, E., Bavasso, F., Cicconi, A., Maccallini, P., Chen, L., Roake, C. M., Schoeftner, S., Artandi, S. E., Gatti, M., Cacchione, S. & Raffa, G. D., Jan 2022, In: FEBS Letters. 596, 1, p. 42-52 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

2021

Alterations of nk cell phenotype in the disease course of multiple myeloma

Pazina, T., Macfarlane, A. W., Bernabei, L., Dulaimi, E., Kotcher, R., Yam, C., Bezman, N. A., Robbins, M. D., Ross, E. A., Campbell, K. S. & Cohen, A. D., Jan 2 2021, In: Cancers. 13, 2, p. 1-22 22 p., 226.

Research output: Contribution to journal › Article › peer-review

Open Access

61 Scopus citations

A novel model of alternative NF-κB pathway activation in anaplastic large cell lymphoma

Wang, H., Wei, W., Zhang, J. P., Song, Z., Li, Y., Xiao, W., Liu, Y., Zeng, M. S., Petrus, M. N., Thomas, C. J., Kadin, M. E., Nakagawa, M., Waldmann, T. A. & Yang, Y., Jul 2021, In: Leukemia. 35, 7, p. 1976-1989 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

ATF3 coordinates serine and nucleotide metabolism to drive cell cycle progression in acute myeloid leukemia

Johnson, N., Di Marcantonio, D., Martinez, E., Kanefsky, J. S., Huhn, J. M., Gabbasov, R., Gupta, A., Krais, J. J., Peri, S., Tan, Y., Skorski, T., Dorrance, A., Garzon, R., Goldman, A. R., Tang, H. Y. & Sykes, S. M., Jul 1 2021, In: Molecular Cell. 81, 13, p. 2752-2764.e6

Research output: Contribution to journal › Article › peer-review

Open Access

54 Scopus citations

Differential effects of clinically relevant N- versus C-terminal truncating CDKN1A mutations on cisplatin sensitivity in bladder cancer

Sikder, R. K., Ellithi, M., Uzzo, R. N., Weader, D. J., Metz, A. L., Behbahani, A., McKenzie, E. R., El-Deiry, W. S. & Abbosh, P., Mar 1 2021, In: Molecular Cancer Research. 19, 3, p. 403-413 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Evaluation of the small-molecule BRD4 degrader CFT-2718 in small-cell lung cancer and pancreatic cancer models

Golemis, E. A., Sun, D., Nikonova, A. S., Zhang, P., Deneka, A. Y., Fitzgerald, M. E., Michael, R. E., Lee, L., Lilly, A. C., Fisher, S. L., Phillips, A. J., Nasveschuk, C. G., Proia, D. A. & Tu, Z., Aug 2021, In: Molecular Cancer Therapeutics. 20, 8, p. 1367-1377 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Ibrutinib and venetoclax target distinct subpopulations of CLL cells: implication for residual disease eradication

Lu, P., Wang, S., Franzen, C. A., Venkataraman, G., McClure, R., Li, L., Wu, W., Niu, N., Sukhanova, M., Pei, J., Baldwin, D., Nejati, R., Wasik, M. A., Khan, N., Tu, Y., Gao, J., Chen, Y., Ma, S., Larson, R. A. & Wang, Y. L., Feb 2021, In: Blood Cancer Journal. 11, 2, p. 39 39.

Research output: Contribution to journal › Article › peer-review

Open Access

45 Scopus citations

Immortalization of human primary prostate epithelial cells via CRISPR inactivation of the CDKN2A locus and expression of telomerase

Zhao, Z., Fowle, H., Valentine, H., Liu, Z., Tan, Y., Pei, J., Badal, S., Testa, J. R. & Grana, X., Mar 2021, In: Prostate Cancer and Prostatic Diseases. 24, 1, p. 233-243 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

Impacts of pembrolizumab therapy on immune phenotype in patients with high-grade neuroendocrine neoplasms

MacFarlane, A. W., Yeung, H. M., Alpaugh, R. K., Dulaimi, E., Engstrom, P. F., Dasari, A. N., Campbell, K. S. & Vijayvergia, N., Jul 2021, In: Cancer Immunology, Immunotherapy. 70, 7, p. 1893-1906 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Cell Culture Facility

Research output

Search results

2023

2022

2021